Journal of Nursing and Midwifery Sciences

CASE REPORT
Year
: 2015  |  Volume : 2  |  Issue : 4  |  Page : 70--74

Alobar holoprosencephaly: A case report


Mehrbanu Amirshahi1, Akram Sanagoo2, Ashraf Salehi3, Azam Kerami3, Abdolghani Abdollahimohammad1, Fatemeh Mirshekari1, Fereshteh Naroei1, Leila Mansoorifar4, Marzeeh Mirshekari5, Leila Mirshekari1 
1 Faculty of Nursing & Midwifery, Zabol University of Medical Sciences, Zabol, Iran
2 Nursing Research Center, Golestan University of Medical Sciences, Golestan, Iran
3 Faculty of Medical Sciences Khomain, Arak University of Medical Sciences, Arak, Iran
4 University of Medical Sciences, Tehran, Iran
5 Zahedan University of Medical Sciences, Zahedan, Iran

Correspondence Address:
Leila Mirshekari
Faculty of Nursing & Midwifery, Zabol University of Medical Sciences, Zabol
Iran

Holoprosencephaly (HPE) is a rare congenital brain malformation associated with multiple midline facial defects. This anomaly is resulted from the failure of diverticulation and cleavage of primitive prosencephalon during weeks 4-8 of gestation. HPE is the most common forebrain developmental anomaly in human with the incidence rate of 0.49-1.2 cases per 10,000-20,000 term births. In this study, we described a case of HPE in a neonate with gestational age of 32 weeks. Antenatal ultrasonographic diagnosis was performed, and the infant was presented with macrocephaly, bilateral microphthalmia, hypotelorism, proboscis and ambiguous genitalia.


How to cite this article:
Amirshahi M, Sanagoo A, Salehi A, Kerami A, Abdollahimohammad A, Mirshekari F, Naroei F, Mansoorifar L, Mirshekari M, Mirshekari L. Alobar holoprosencephaly: A case report.J Nurs Midwifery Sci 2015;2:70-74


How to cite this URL:
Amirshahi M, Sanagoo A, Salehi A, Kerami A, Abdollahimohammad A, Mirshekari F, Naroei F, Mansoorifar L, Mirshekari M, Mirshekari L. Alobar holoprosencephaly: A case report. J Nurs Midwifery Sci [serial online] 2015 [cited 2019 Dec 14 ];2:70-74
Available from: http://www.jnmsjournal.org/article.asp?issn=2345-5756;year=2015;volume=2;issue=4;spage=70;epage=74;aulast=Amirshahi;type=0